Baclofen: uses, delivery and evidence

What is baclofen?

This muscle relaxant acts on the nervous system to reduce spasticity. It acts through GABA-related pathways and is commonly an initial medication option for SCI-related spasticity.

How is baclofen used?

Treatment may use tablets or an implanted pump, with individually prescribed dosing and monitoring. A pump delivers medication into fluid around the spinal cord, requires surgery and needs regular refilling and review.

Are there restrictions or precautions for using baclofen?

Other illnesses, pregnancy and medications may affect suitability; assessment is essential. Kidney, breathing or neurological problems and other medicines can be especially relevant to the assessment.