A clinician selects injection sites and doses; effects develop over time and are temporary. Several injections may be needed in one session, with the procedure tailored to the affected muscles or bladder.
The treatment blocks nerve chemicals that normally trigger muscle contraction. The same mechanism can reduce bladder spasms or relax an overactive sphincter, depending on injection location.
Are there restrictions or precautions for using botulinum toxin?
Medical conditions, allergies, infection and costs can affect suitability. Other neuromuscular disorders and infection at the proposed injection site are important concerns.
Evidence is moderate for reducing targeted spasticity and strong for overactive bladder symptoms. Fewer autonomic dysreflexia episodes have been observed, but direct prevention is unproven.
